DYNAMIC CONTROL OF HYDROGEL PROPERTIES VIA ENZYMATIC REACTIONS
Dustin Michael Moore
10.25394/PGS.8025614.v1
https://hammer.purdue.edu/articles/thesis/DYNAMIC_CONTROL_OF_HYDROGEL_PROPERTIES_VIA_ENZYMATIC_REACTIONS/8025614
Two Systems were designed. The first permits tunable on-demand softening of a hydrogel network. The second permits reversible on demand ligand exchange within a hydrogel network. Both means were shown to be cytocompatible and their uses demonstrated in cell culture of mesenchymal stem cells and 3T3 fibroblast cells.
2019-06-10 20:37:25
Tissue engineering
hydrogel
softening
Sortase A
Ligand Exchange
Mesenchymal Stem Cells
3T3 Fibroblast Cells
Biomechanical Engineering